KEY PUBLICATIONS
Submitted and Published Papers
2023
Rosa-Caldwell ME, Mortreux M, Wadhwa A, Kaiser UB, Sung DM, Bouxsein ML, Rutkove SB. "Sex differences in muscle health in simulated micro- and partial-gravity environments in rats". Sports Medicine and Health Science, in press.
Rosa-Caldwell ME, Mortreux M, Wadhwa A, Kaiser UB, Sung DM, Bouxsein ML, Rutkove SB. “Influence of gonadectomy on muscle health in micro and partial-gravity environments in rats” Journal of Applied Physiology 2023 June 1;134(6):1438-429. DOI: 10.1152/japplphysiol.00023.2023
2022
Swain P, Mortreux M, Laws JM, Kyriacou H, De Martino E, Winnard A, Caplan N. “Bone deconditioning during partial weight-bearing in rodents – a systematic review and meta-analysis”. Life Sciences in Space Research, https://doi.org/10.1016/j.lssr.2022.07.003
Swain P, Mortreux M, Laws JM, Kyriacou H, De Martino E, Winnard A, Caplan N. “Skeletal muscle deconditioning during partial weight-bearing in rodents – systematic review and meta-analysis”. Life Sciences in Space Research, https://doi.org/10.1016/j.lssr.2022.06.007
Mortreux M, Nagy JA, Zhong H, Sung DM, Concepcion HA, Leitner M, Dalle Pazze L, Rutkove SB. “Performing in vivo and ex vivo electrical impedance myography in rodents”. J Vis Exp – June 2022. doi:10.3791/63513
2021
Mortreux M, Rosa-Caldwell ME, Stiehl ID, Sung DM, Thomas NT, Fry CS & Rutkove SB. “Hindlimb suspension in Wistar rats: sex-based differences in muscle response”. Physiological Reports, 2021 Oct;9(19):e15042. doi:10.14814/phy2.15042.
Rosa-Caldwell ME, Mortreux M, Sung DM, Bouxsein ML, Kaiser U, Dunlap K, Greene NP, Rutkove SB. “The estrus cycle and skeletal muscle atrophy: investigations in rodent models of muscle loss”. Exp Physiol 2021 Sep 26. doi:10.1113/EP089962.
Swain P, Mortreux M, Rosa-Caldwell ME, Winnard A. “Rodent Partial Weight-Bearing Model: Risk of Bias Checklist”. Research Gate Sep 2021. doi:10.13140/RG.2.2.32990.77126/1.
Pandeya SR, Nagy JA, Riveros D, Semple C, Taylor RS, Mortreux M, Sanchez B, Kapur K, Rutkove SB. “Estimating myofiber cross-sectional area and connective tissue deposition with electrical impedance myography: a study in D2-mdx mice”. Muscle Nerve 2021 Jun;63(6):941-950. doi:10.1002/mus.27240.
Willey JS, Britten RA, Blaber E, Tahimic CGT, Chancellor J, Mortreux M, Sanford LD, Kubik AJ, Delp MD, Mao XW. “The individual and combined effects of spaceflight radiation and microgravity on biological systems and functional outcomes”. J Environ Sci Health C Toxicol Carcinog 2021;39(2):129-179. doi:10.1080/26896583.2021.1885283.
2020
Malkani S, Chin CR, Cekanaviciute E, Mortreux M, Okinula H, Tarbier N, Schreurs AAS, Shorazi-Fard Y, Tahimic CGT, Rodriguew DR, Sexton BS, Butler D, Verma A, Bezdan D, Durmaz C, MacKay M, Malnick A, Meydan C, Li S, Garrett-Bakelman F, Fromm B, Afshinnekoo E, Langhorst BW, Dimalanta ET, Cheng-Campbell M, Blaber E, Schisler JC, Venderburg C, Friedlander MR, McDonald JT, Costes SV, Rutkove S, Grabham P, Mason CR, Beheshti A. “Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development”. Cell Reports 2020 Nov 21;108448 doi:10.1016/j.celrep.2020.108448.
Pandeya S, Nagy JA, Riveros D, Semple C, Taylor R, Mortreux M, Sanchez B, Kapur K, Rutkove SB. “Predicting myofiber cross-sectional area and triglyceride content with electrical impedance myography: a study in db/db mice”. Muscle Nerve 2020 doi:10.1002/mus.27095.
Mortreux M and Rosa-Caldwell ME. “Approaching gravity as a continuum using the rat partial weight-bearing model”. Life 2020 10(10), 235 https://doi.org/10.3390/life10100235.
Semple C, Riveros D, Sung D-S, Nagy JA, Rutkove SB, Mortreux M. “Using electrical impedance myography as a biomarker of muscle deconditioning in rats exposed to micro- and partial- gravity analogs”. Frontiers in Physiology 2020 doi: 10.3389/fphys.2020.557796.
McIlduff CE, Martucci MG, Shin C, Qi K, Pacheck AK, Gutierrez H, Mortreux M, Rutkove SB. “Quantitative ultrasound of the tongue: echo intensity is a potential biomarker of bulbar dysfunction in amyotrophic lateral sclerosis” Clinical Neurophysiology 2020 Jul 17;131(10):2423-2428. DOI: 10.1016/j.clinph.2020.06.027
Ko FC, Mortreux M, Riveros D, Nagy JA, Rutkove SB, Bouxsein MB. “Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats” Npj Microgravity 2020 May 18;6:15. DOI: 10.1038/s41526-020-0105-0
Semple C, Riveros D, Nagy JA, Rutkove SB, Mortreux M. “Partial Weight-Bearing in Female Rats: Proof of Concept in a Martian-Gravity Analog” Frontiers in Physiology 2020 Apr 3;11:302. DOI: 10.3389/fphys.2020.00302
Mortreux M, Riveros D, Semple C, Bouxsein ML, Rutkove SB. “The partial weight-bearing rat model using a pelvic harness does not impact stress or hindlimb blood flow” Acta Astronautica 2020 (168):249-255.https://doi.org/10.1016/j.actaastro.2019.12.024
2019
Mortreux M, Foppen E, Denis RG, Montaner M, Kassis N, Denom J, Vincent M, Fumeron F, Kujawski-Lafourcade M, Andreelli F, Balkau B, Marre M, Roussel R, Magnan C, Gurden H, Migrenne-Li S. “New roles for Prokineticin-2 in feeding behavior, insulin resistance and type 2 diabetes: studies in mice and humans” Molecular Metabolism 2019 Nov (29):182-196. DOI: 10.1016/j.molmet.2019.08.016
Mortreux M, Semple C, Riveros D, Nagy JA, Rutkove SB. “Electrical impedance myography for the detection of muscle inflammation induced by λ-carrageenan”. PLoS One 2019 Oct 1;14(10):e0223265. DOI: 10.1371/journal.pone.0223265
Mortreux M, Ko FC, Riveros D, Bouxsein ML, Rutkove SB. “Longitudinal time course of muscle impairments during partial weight-bearing in rats” Npj Microgravity 2019 Aug 22;5:20. DOI: 10.1038/s41526-019-0080-5
Mortreux M, Riveros D, Bouxsein ML, Rutkove SB. “A moderate daily dose of resveratrol mitigates musle deconditioning in a Martian gravity analog” Frontiers in Physiology 2019 Jul 18;10:899. DOI: 10.3389/fphys.2019.00899
Mortreux M, Riveros D, Bouxsein ML, Rutkove SB. “Mimicking a space mission to Mars using hindlimb unloading and partial weight-bearing” Journal of Visualized Experiments 2019 Apr 4;(146):59327. DOI: 10.3791/59327
2018
Mortreux M, Nagy JA, Ko FC, Bouxsein ML, Rutkove SB. “A novel partial gravity ground-based analog for rats via quadrupedal unloading” Journal of Applied Physiology 2018 Jul 1;125(1):175-182. DOI: 10.1152/japplphysiol.01083.2017
2016
Renon M, Legrand B, Blanc E, Daubigney F, Bokobza C, Mortreux M, Paul JL, Delabar JM, Rouach H, Andreau K, Janel N. “Impact of Dyrk1A level on alcohol metabolism”. Biochimica Biophysica Acta 2016 Sep;1862(9):1495-503. DOI: 10.1016/j.bbadis.2016.05.011
2014
Abou-Khalil R, Yang F, Mortreux M, Lieu S, Yu YY, Wurmser M, Pereira C, Relaix F, Miclau T, Marcucio RS, Colnot C. “Delayed bone regeneration is linked to chronic inflammation in murine muscular dystrophy”. Journal of Bone and Mineral Research 2014 Feb;29(2):304-15. DOI: 10.1002/jbmr.2038